- Ira Louvin – country singer/songwriter/mandolinist – The Louvin Brothers – (4/21/1924 – 6/20/1965)
- Eddie King – Chicago blues guitarist/singer/songwriter – (4/21/1938 – 3/14/2012)
- Pee Wee Ellis – jazz-funk-soul saxophone/keyboards/flute/composer – associated acts include – James Brown – Van Morrison – (4/21/1941 – 9/23/2021)
- Howard “Sparky” Childress – guitarist – early rock-rockabilly group – Joe Bennett and The Sparkletones – best known for 1957 hit – Black Slacks – (4/21/1943 – 11/30/2019)
- Alan Warner – guitarist/songwriter – best known as a founding member of – The Foundations – 1947
- Iggy Pop – punk rock singer – The Stooges – solo artist – 1947
- John Weider – bass/guitar/violin – best known as guitarist with Eric Burdon and the Animals (1966-1968) – bassist with Family (1969-1971) – 1947
- Paul Davis – singer/songwriter/keyboards/piano – hits include – I Go Crazy – 65 Love Affair – Ride ‘Em Cowboy – Cool Night – (4/21/1948 – 4/22/2008)
- Nickey Barclay – keyboards/vocals – best known will all female rock group – Fanny – 1951
- Robert Gotobed (Robert Grey) – punk rock drummer – best known with – Wire – 1951
- Mike Barson – songwriter/composer/multi-instrumentalist – best known with – Madness – 1958
- Jerry Only – bassist/vocals – best known with punk-metal group – The Misfits – 1959
- Michael Timmins – songwriter/guitarist – Canadian alt-rock group – Cowboy Junkies – songs include – Sweet Jane – Sun Comes Up, It’s Tuesday Morning – A Common Disaster – 4/21/1959
- Robert Smith – English alternative rock singer/songwriter/guitar/bass/keyboards/producer – The Cure – 2019 Rock and Roll Hall of Fame – group hits include – Just Like Heaven – Lovesong – Friday I’m In Love – associated acts include – Cult Hero – The Glove – Siouxsie and the Banshees – 1959
- John Maher – drummer – best known with punk-new wave group – Buzzcocks – 1960
- Johnny McElhone – guitarist/songwriter – associated acts include – associated acts include – Hipsway – Texas – Altered Images – 1963
- Michael Franti – singer/poet/rapper/guitar – Michael Franti and Spearhead – The Beatnigs – The Disposable Heroes of Hiphoprisy – 1966
- Glen Hansard – folk-rock singer/songwriter/guitar/piano/mandolin/actor – associated acts include – The Swell Season – The Frames – 1970
- Branden Steineckert – drummer – best known with punk groups – Rancid – The Used – 1978
- Jukka “Julius” Nevalainen – drummer – best known with symphonic metal group – Nightwish – 1978
- Christian “CC” Coma – drummer – Black Veil Brides – 1985
- Zack Merrick – bassist/backing vocals – All Time Low – 1988
- Sydney Sierota – singer/keyboards – alt-pop band – Echosmith – 1997